In July 2022, the European Commission sent requests to EFSA to provide scientific opinions on the safety of three substances according to article 8 of Regulation (EC) 1925/2006:

• Berberine (and plant preparations containing it), following a request by the French authorities
• Hydroxycitric Acid (and plant preparations containing it, particularly Garcinia gummi-gutta), following a request by the Spanish authorities
• Bitter and sweet fennel (presence of estragole), following a request by the German authorities.

EFSA has accepted these three requests in November and should provide those scientific opinions in May 2025 at the latest.